Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049009 | 0.84 | CYP19A1 (0.36) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL3063635 | 0.82 | LMNA (0.54) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL8397725 | 0.81 | ALDH1A1 (0.45) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL5693171 | 0.78 | LMNA (0.50) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL27725358 | 0.77 | LMNA (0.58) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL11543059 | 0.74 | LMNA (0.55) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL13250874 | 0.73 | LMNA (0.54) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL7357435 | 0.73 | ALDH1A1 (0.53) | LMNAALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL6133452 | 0.72 | SRR (0.47) | LMNAALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL212215 | 0.72 | ALDH1A1 (0.51) | LMNACA12CA9ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370283-B1 | Process for preparing 63-carboxyamides of teicoplanin antibiotics | LEPETIT SPA (IT) | 1994-06-15 | — | — | EP | claimed |
| EP-0370283-A2 | Process for preparing 63-carboxyamides of teicoplanin antibiotics | GRUPPO LEPETIT S.p.A. (IT) | 1990-05-30 | — | — | EP | claimed |