Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688991 | 0.75 | ESR1 (0.45) | ESR1ACP3CRHBPCRHR2TSHR | |
| SCHEMBL1538376 | 0.74 | RIPK1 (0.42) | ESR1MAPK1ESR2LMNAALDH1A1 | |
| SCHEMBL17101272 | 0.73 | ACP3 (0.42) | ESR1ACP3LMNAKMT2AALDH1A1 | |
| SCHEMBL9280762 | 0.73 | SLC6A2 (0.37) | ESR1MAPK1ESR2TSHRACHE | |
| SCHEMBL6546306 | 0.73 | ESR1 (0.56) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL23735916 | 0.72 | ESR1 (0.46) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL6277396 | 0.72 | KEAP1 (0.40) | MAPK1TSHRACHEMEN1LMNA | |
| SCHEMBL9279074 | 0.71 | MAPK1 (0.46) | ESR1MAPK1ESR2TSHRMAPT | |
| SCHEMBL575235 | 0.71 | MAPK1 (0.46) | ESR1MAPK1ESR2TSHRMAPT | |
| Water SCHEMBL3656564 | 0.71 | ESR1 (0.54) | ESR1ACP3TSHRACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421340-B1 | Method for producing 1,1-diarylethanes | KUREHA CHEMICAL IND CO LTD (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5068482-A | Reaction of styrene derivatives with benzene by alkylation with a zeolite catalyst | KUREHA KAGAKU KOGYO K.K. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0421340-A1 | Method for producing 1,1-diarylethanes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-10 | — | — | EP | disclosed |