SCHEMBL9280762

SCHEMBL9280762

Cc1cc(C)c(C(C)C(C)(C)c2ccccc2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
ESR1 P03372 3/20 0.37
ESR2 Q92731 3/20 0.37
FFAR4 Q5NUL3 1/20 0.36
LMNA P02545 3/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ALOX15 P16050 1/20 0.31
NR3C1 P04150 1/20 0.31
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277396 0.73 KEAP1 (0.40) LMNAMEN1KMT2AMAPK1ALDH1A1
SCHEMBL9345237 0.73 ESR1 (0.42) SLC6A2SLC6A4SLC6A3ESR1ESR2
SCHEMBL1538376 0.71 RIPK1 (0.42) SLC6A4SLC6A3ESR1ESR2LMNA
SCHEMBL6281493 0.69 TSHR (0.43) SLC6A4SLC6A3LMNAMEN1KMT2A
SCHEMBL9279226 0.68 SLC6A2 (0.49) SLC6A2SLC6A4SLC6A3FFAR4LMNA
SCHEMBL575235 0.68 MAPK1 (0.46) ESR1ESR2MAPTKMT2ACYP1A2
SCHEMBL9279074 0.68 MAPK1 (0.46) ESR1ESR2MAPTKMT2ACYP1A2
SCHEMBL4352236 0.66 MAPK1 (0.44) ESR1ESR2MAPTKMT2ACYP1A2
SCHEMBL2429063 0.66 ALDH1A1 (0.46) SLC6A4ESR1ESR2LMNAMAPT
Tert-Butylbenzene SCHEMBL11183915 0.66 TSHR (0.55) ESR1ESR2LMNAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652923-A4 LIQUID SCINTILLATION MEDIUM WITH A 1,2-DICUMYLETHANE SOLVENT. MIRSKY JEFFREY (US) 1995-10-11 EP disclosed
EP-0652923-A1 LIQUID SCINTILLATION MEDIUM WITH A 1,2-DICUMYLETHANE SOLVENT MIRSKY, Jeffrey (US) 1995-05-17 EP disclosed
WO-1994003552-A1 LIQUID SCINTILLATION MEDIUM WITH A 1,2-DICUMYLETHANE SOLVENT MIRSKY JEFFREY (US) 1994-02-17 WO disclosed