SCHEMBL6277396

SCHEMBL6277396

Cc1ccc(C(C)C(C)(C)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
ALOX12 P18054 1/20 0.39
ACHE P22303 1/20 0.39
KIF11 P52732 6/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.34
CHRNA7 P36544 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6281493 0.92 TSHR (0.43) LMNATSHRALOX12ACHEKIF11
SCHEMBL1538376 0.87 RIPK1 (0.42) LMNAMAPK1ALDH1A1
SCHEMBL6048332 0.80 MAPK1 (0.35) MAPK1ALDH1A1KMT2A
SCHEMBL18884474 0.77 PTPN5 (0.42) LMNATSHRALOX12ALDH1A1
SCHEMBL28953183 0.77 KEAP1 (0.39) KEAP1NFE2L2LMNATSHRKIF11
SCHEMBL7737041 0.76 RIPK1 (0.37) LMNAMAPK1ALDH1A1
SCHEMBL3482030 0.74 KEAP1 (0.37) KEAP1NFE2L2LMNATSHRALOX12
SCHEMBL30949389 0.73 CHRNA7 (0.42) LMNATSHRACHESMN1; SMN2ALDH1A1
SCHEMBL6548164 0.73 LMNA (0.50) KEAP1NFE2L2LMNATSHRALOX12
SCHEMBL9280762 0.73 SLC6A2 (0.37) LMNATSHRALOX12ACHEMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-9056227-B2 Golf ball comprising a core having a shallow hardness gradient ACUSHNET COMPANY (US) 2015-06-16 US disclosed
US-8968117-B2 Dual-core comprising zero gradient center and positive gradient outer core layer ACUSHNET COMPANY (US) 2015-03-03 US disclosed
US-20130109506-A1 GOLF BALL COMPRISING A CORE HAVING A SHALLOW HARDNESS GRADIENT ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-20130109504-A1 DUAL-CORE COMPRISING ZERO GRADIENT CENTER AND POSITIVE GRADIENT OUTER CORE LAYER ACUSHNET COMPANY (US) 2013-05-02 US disclosed
US-6967229-B2 Carbon-carbon initiators for use in golf balls ACUSHNET COMPANY (US) 2005-11-22 US disclosed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0421340-B1 Method for producing 1,1-diarylethanes KUREHA CHEMICAL IND CO LTD (JP) 1994-07-13 EP disclosed
US-5068482-A Reaction of styrene derivatives with benzene by alkylation with a zeolite catalyst KUREHA KAGAKU KOGYO K.K. (JP) 1991-11-26 US disclosed
EP-0421340-A1 Method for producing 1,1-diarylethanes KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-04-10 EP disclosed
EP-0015758-A1 Process for producing styrenes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-09-17 EP disclosed