Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340530 | 0.88 | CDK1 (0.43) | KMT2AALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL2987423 | 0.87 | ALDH1A1 (0.46) | KMT2AHTTALDH1A1LMNAHSD17B10 | |
| SCHEMBL8446516 | 0.85 | NPC1 (0.54) | KMT2AALDH1A1LMNANPC1RAB9A | |
| SCHEMBL17581241 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL17589003 | 0.81 | HTR7 (0.46) | KMT2ANUDT1POLBMAPTADORA2A | |
| SCHEMBL31403787 | 0.80 | ALDH1A1 (0.45) | HTTALDH1A1LMNAHSD17B10NPC1 | |
| SCHEMBL11099815 | 0.80 | NUDT1 (0.62) | KMT2AHTTALDH1A1LMNAHSD17B10 | |
| SCHEMBL5915041 | 0.79 | ALDH1A1 (0.54) | KMT2AHTTALDH1A1LMNAHSD17B10 | |
| SCHEMBL2990823 | 0.77 | CDK1 (0.46) | KMT2AHTTALDH1A1LMNAHSD17B10 | |
| SCHEMBL8448250 | 0.75 | KMT2A (0.51) | KMT2AALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0378092-B1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF AG (DE) | 1994-05-11 | — | — | EP | disclosed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |
| EP-0378092-A1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |