Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10787325 | 0.84 | FOLH1 (0.47) | HSD17B10NPC1RAB9A | |
| SCHEMBL21486 | 0.84 | HNF4A (0.52) | AKR1C3AKR1C2AKR1C1KDM4EALDH1A1 | |
| SCHEMBL6868591 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EHSD17B10ALDH1A1NPC1 | |
| SCHEMBL17744783 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2MCL1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2394811 | 0.82 | AKR1C2 (0.44) | AKR1C3AKR1C2AKR1C1KMT2AMEN1 | |
| SCHEMBL11430860 | 0.82 | PRKAB2 (0.46) | SMN1; SMN2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6884345 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2AKR1C3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL988420 | 0.81 | MCL1 (0.47) | SMN1; SMN2MCL1AKR1C3PRKAB2PRKAG1 | |
| SCHEMBL6870968 | 0.80 | EGFR (0.50) | SMN1; SMN2KDM4EHSD17B10ALDH1A1GAA | |
| SCHEMBL27024028 | 0.78 | HNF4A (0.48) | MCL1AKR1C3AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318027-B1 | Fluororubber-containing powder coating composition | DAIKIN IND LTD (JP) | 1994-07-06 | — | — | EP | claimed |
| US-4628336-A | POLYPHENYL ESTERS; SOIL RESISTANCE; IMAGE STABILITY | JUJO PAPER CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
| EP-0036385-B1 | INSECTICIDAL VAPOUR-EMITTING COMPOSITIONS ON THE BASIS OF PYRETHRINOIDS | Airwick AG (CH) | 1984-05-02 | — | — | EP | disclosed |
| EP-0036385-A2 | Insecticidal vapour-emitting compositions on the basis of pyrethrinoids | Airwick AG (CH) | 1981-09-23 | — | — | EP | disclosed |