SCHEMBL27024028

SCHEMBL27024028

O=C(O)c1ccc(-c2ccc(C(=O)O)c(C(=O)O)c2-c2ccccc2)c(-c2ccccc2)c1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 3/20 0.48
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 1/20 0.44
CDC25B P30305 2/20 0.44
ACMSD Q8TDX5 2/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
FOLH1 Q04609 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
THRB P10828 1/20 0.42
MAPK1 P28482 1/20 0.42
RECQL P46063 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 2/20 0.42
PTPN1 P18031 1/20 0.42
WDR5 P61964 1/20 0.41
AKR1C3 P42330 2/20 0.41
FABP3 P05413 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21486 0.94 HNF4A (0.52) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL30395913 0.88 WDR5 (0.48) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL6755748 0.88 WDR5 (0.48) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL3807758 0.86 ACMSD (0.45) HNF4AALDH1A1ALOX15CDC25BACMSD
Ethylenediamine SCHEMBL28403779 0.85 HNF4A (0.44) HNF4AALDH1A1CDC25BACMSDATM
SCHEMBL87698 0.84 MAPT (0.52) HNF4AALDH1A1ALOX15CDC25BLMNA
Biphenyl SCHEMBL11750014 0.84 HNF4A (0.54) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL2748060 0.83 HNF4A (0.53) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL6114449 0.83 PTPN1 (0.46) HNF4AALDH1A1ALOX15CDC25BACMSD
SCHEMBL29945054 0.82 ACMSD (0.52) HNF4AALDH1A1ALOX15CDC25BACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11879039-B1 Preparation method for thermoplastic multi-hybrid polyimide films HARBIN ENGINEERING UNIVERSITY (CN) 2024-01-23 US claimed
US-11879039-B1 Preparation method for thermoplastic multi-hybrid polyimide films HARBIN ENGINEERING UNIVERSITY (CN) 2024-01-23 US disclosed