Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 7/20 | 0.34 |
| ▸ | ACE | P12821 | 7/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933898 | 0.77 | CYP17A1 (0.49) | EPHX1TBXAS1 | |
| SCHEMBL26167691 | 0.77 | SRR (0.54) | MMEACESRRPSAT1GPR88 | |
| SCHEMBL933922 | 0.74 | MKNK1 (0.55) | TBXAS1 | |
| SCHEMBL12118748 | 0.71 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL22593510 | 0.71 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL23643109 | 0.71 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL14032489 | 0.71 | TAAR1 (0.59) | EPHX1ACE | |
| SCHEMBL22937469 | 0.71 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL23643108 | 0.71 | EPHX1 (0.50) | EPHX1 | |
| SCHEMBL934530 | 0.71 | TAAR1 (0.59) | EPHX1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |