Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809554 | 0.86 | ALDH1A1 (0.44) | ALDH1A1APEX1LMNAALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL5704139 | 0.83 | ALDH1A1 (0.48) | ALDH1A1APEX1LMNAALKBH5SUCNR1 | |
| SCHEMBL4459492 | 0.81 | ALDH1A1 (0.42) | ALDH1A1APEX1LMNAALKBH5SUCNR1 | |
| SCHEMBL28245171 | 0.80 | APEX1 (0.41) | ALDH1A1APEX1LMNAALKBH5SUCNR1 | |
| SCHEMBL9165562 | 0.79 | LMNA (0.36) | ALDH1A1LMNAEPHX1CTSDBACE1 | |
| SCHEMBL6406451 | 0.78 | POLB (0.40) | ALDH1A1LMNAEPHX2EPHX1POLB | |
| SCHEMBL8142390 | 0.76 | CA12 (0.33) | EPHX2POLBRAB9A | |
| SCHEMBL777574 | 0.75 | CA1 (0.33) | — | |
| SCHEMBL2951024 | 0.73 | CA1 (0.32) | — | |
| SCHEMBL8147652 | 0.72 | EPHX1 (0.33) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334287-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | Università Degli Studi Di Torino (IT) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022234447-A1 | NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2022-11-10 | — | — | WO | disclosed |
| US-5364959-A | Storage stable compounds for detergents as bleaches | MONSANTO COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5004558-A | Bleaching detergent composition; storage stabiklity; less dye damage | MONSANTO COMPANY (US) | 1991-04-02 | — | — | US | disclosed |
| EP-0329013-A2 | Renin-inhibiting amino acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4824591-A | BLEACHES, DETERGENTS | MONSANTO COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| US-4758369-A | Sulfone peroxycarboxylic acids | MONSANTO COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0267175-A2 | Sulfone peroxycarboxylic acids | Monsanto Company (US) | 1988-05-11 | — | — | EP | disclosed |