Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455429 | 0.80 | ALDH1A1 (0.34) | ALDH1A1CES2CES1EPHX2EPHX1 | |
| SCHEMBL11480211 | 0.80 | ALDH1A1 (0.34) | ALDH1A1CES2CES1EPHX2EPHX1 | |
| SCHEMBL22333370 | 0.80 | ALDH1A1 (0.34) | ALDH1A1CES2CES1EPHX2EPHX1 | |
| SCHEMBL9345595 | 0.78 | ALDH1A1 (0.46) | POLBALDH1A1LMNAEPHX2EPHX1 | |
| SCHEMBL3311509 | 0.78 | LMNA (0.35) | LMNACES2CES1EPHX2EPHX1 | |
| Succinic Acid SCHEMBL5704139 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNACES2CES1EPHX2 | |
| SCHEMBL10982764 | 0.77 | MMP1 (0.32) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL21753714 | 0.77 | MMP1 (0.32) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL23571037 | 0.75 | POLB (0.34) | POLB | |
| SCHEMBL8528985 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1LMNAEPHX1MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | disclosed |
| US-4637833-A | OIL WELLS, GAS WELLS | PHILLIPS PETROLEUM CO. (US) | 1987-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | POLB 2445/4885ALDH1A1 345/4885LMNA 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.