Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364796 | 0.82 | GNAI3 (0.58) | GNAI3GNAO1GNAI1HTTCNR1 | |
| SCHEMBL2997271 | 0.82 | GNAI3 (0.42) | GNAI3GNAO1GNAI1HTTCNR1 | |
| SCHEMBL16405435 | 0.80 | GNAI3 (0.60) | GNAI3GNAO1GNAI1CNR1CNR2 | |
| SCHEMBL16010753 | 0.79 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR1CNR2 | |
| SCHEMBL271765 | 0.79 | GNAI3 (0.41) | GNAI3GNAO1GNAI1HTTCNR1 | |
| SCHEMBL3974367 | 0.79 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR1CNR2 | |
| SCHEMBL3868277 | 0.79 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR1CNR2 | |
| SCHEMBL15054982 | 0.78 | HTT (0.41) | GNAI3GNAO1GNAI1HTTCNR1 | |
| SCHEMBL15055493 | 0.78 | HTT (0.41) | GNAI3GNAO1GNAI1HTTCNR1 | |
| SCHEMBL2364252 | 0.78 | TP53 (0.50) | GNAI3GNAO1GNAI1HTTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |