Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271770 | 0.89 | HTT (0.41) | GNAI3GNAO1GNAI1HTTCNR2 | |
| SCHEMBL9345633 | 0.79 | GNAI3 (0.44) | GNAI3GNAO1GNAI1HTTCNR2 | |
| SCHEMBL24354751 | 0.79 | ALDH1A1 (0.50) | GNAI3GNAO1GNAI1HTTCNR2 | |
| SCHEMBL2364796 | 0.78 | GNAI3 (0.58) | GNAI3GNAO1GNAI1HTTCNR2 | |
| SCHEMBL2997271 | 0.78 | GNAI3 (0.42) | GNAI3GNAO1GNAI1HTTCNR2 | |
| SCHEMBL265501 | 0.77 | ALDH1A1 (0.50) | GNAI3GNAO1GNAI1HTTALDH1A1 | |
| SCHEMBL16405435 | 0.76 | GNAI3 (0.60) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL16010753 | 0.75 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL3868277 | 0.75 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL3974367 | 0.75 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133888-B2 | Hydrazide containing taxane conjugates | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-03-13 | — | — | US | disclosed |
| US-8133888-B2 | Hydrazide containing taxane conjugates | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-03-13 | — | — | US | disclosed |
| US-20110172226-A1 | NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2011-07-14 | — | — | US | disclosed |
| US-20110172226-A1 | NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172226-A1 | NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-3, H1-5 | GNAI3 3216/4885GNAO1 1782/4885GNAI1 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.