Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346876 | 0.90 | HRH3 (0.39) | DRD2HTR1AHTR2ADRD3ALDH1A1 | |
| SCHEMBL9349805 | 0.90 | SMN1; SMN2 (0.41) | DRD2HTR1AHTR2ADRD3NFE2L2 | |
| SCHEMBL9349897 | 0.87 | SMN1; SMN2 (0.39) | DRD2HTR1AHTR2ADRD3ALDH1A1 | |
| SCHEMBL9349827 | 0.85 | HTR1A (0.51) | DRD2HTR1AHTR2ADRD3HRH3 | |
| SCHEMBL9345654 | 0.85 | ALDH1A1 (0.50) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9344861 | 0.83 | HTR1A (0.44) | DRD2HTR1AHTR2ADRD3DRD1 | |
| SCHEMBL9346842 | 0.80 | HRH3 (0.40) | DRD2POLBNFE2L2ALDH1A1HRH3 | |
| SCHEMBL9344884 | 0.80 | HRH3 (0.40) | DRD2NFE2L2ALDH1A1HRH3HRH1 | |
| SCHEMBL9346897 | 0.80 | HTR1A (0.39) | DRD2HTR1AHTR2ADRD3ALDH1A1 | |
| SCHEMBL9349853 | 0.80 | LMNA (0.42) | DRD2HTR1AHTR2ADRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |