Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349813 | 0.89 | TSHR (0.48) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9346878 | 0.89 | TSHR (0.48) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9349900 | 0.86 | TSHR (0.50) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9349856 | 0.85 | HTR7 (0.49) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9345642 | 0.85 | DRD2 (0.40) | ALDH1A1GAAKDM4EHTR7KCNH2 | |
| SCHEMBL9349836 | 0.83 | HTR7 (0.51) | ALDH1A1GAATSHRALOX15HTR7 | |
| SCHEMBL9344863 | 0.82 | ALOX15 (0.48) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9344888 | 0.79 | TSHR (0.48) | ALDH1A1GAATSHRALOX15KDM4E | |
| SCHEMBL9346847 | 0.79 | TSHR (0.48) | ALDH1A1TSHRALOX15KDM4EHTR7 | |
| SCHEMBL9346901 | 0.79 | HTR7 (0.42) | ALDH1A1TSHRALOX15KDM4EHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326870-A | Asthma; bronchodilator agents; respiratory system disorders | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | disclosed |