Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | JMJD6 | Q6NYC1 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406007 | 0.86 | JMJD6 (0.59) | SMN1; SMN2JMJD6LMNAPIK3CAALDH1A1 | |
| SCHEMBL930636 | 0.86 | JMJD6 (0.57) | SMN1; SMN2JMJD6LMNAPIK3CAJMJD7 | |
| SCHEMBL29466587 | 0.86 | JMJD6 (0.57) | SMN1; SMN2JMJD6LMNAPIK3CAJMJD7 | |
| SCHEMBL17518838 | 0.85 | JMJD6 (0.59) | SMN1; SMN2JMJD6LMNAPIK3CAKDM4E | |
| SCHEMBL9561789 | 0.85 | TSHR (0.47) | JMJD6PIK3CAJMJD7CA12CA1 | |
| SCHEMBL8408330 | 0.84 | L3MBTL1 (0.55) | SMN1; SMN2JMJD6LMNAALDH1A1KDM4E | |
| SCHEMBL4582464 | 0.78 | L3MBTL1 (0.57) | SMN1; SMN2JMJD6ALDH1A1KDM4EKDM6B | |
| SCHEMBL17798294 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNASERPINE1ALDH1A1TSHR | |
| SCHEMBL9561675 | 0.78 | MAPT (0.45) | JMJD6LMNASERPINE1ALDH1A1KDM4E | |
| SCHEMBL9345729 | 0.78 | LMNA (0.58) | SMN1; SMN2LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |