Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202083 | 0.91 | TSHR (0.45) | TSHRJMJD6KMT2AMAPTKDM4E | |
| SCHEMBL8406007 | 0.86 | JMJD6 (0.59) | TSHRJMJD6MAPTKDM4EKDM6B | |
| SCHEMBL9345772 | 0.85 | SMN1; SMN2 (0.50) | TSHRJMJD6MAPTKDM4EKDM6B | |
| SCHEMBL726595 | 0.83 | RECQL (0.47) | TSHRKMT2AMAPTALDH1A1CA12 | |
| SCHEMBL8408330 | 0.83 | L3MBTL1 (0.55) | TSHRJMJD6KMT2AMAPTKDM4E | |
| SCHEMBL29466587 | 0.82 | JMJD6 (0.57) | JMJD6KMT2AKDM5CKDM4CKDM5B | |
| SCHEMBL930636 | 0.82 | JMJD6 (0.57) | JMJD6KMT2AKDM5CKDM4CKDM5B | |
| SCHEMBL4582464 | 0.81 | L3MBTL1 (0.57) | TSHRJMJD6KMT2AMAPTKDM4E | |
| SCHEMBL9561561 | 0.80 | KDM4E (0.44) | TSHRJMJD6KMT2AMAPTKDM4E | |
| SCHEMBL9561675 | 0.80 | MAPT (0.45) | JMJD6KMT2AMAPTKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |