Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933473 | 0.86 | PRMT6 (0.61) | PRMT6AOC3MAPTEPHX1KLKB1 | |
| SCHEMBL933924 | 0.86 | LMNA (0.61) | LMNAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22501576 | 0.85 | EPHX2 (0.64) | EPHX2PRMT6LMNAAOC3BACE1 | |
| SCHEMBL31321081 | 0.84 | MAPT (0.69) | LMNAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10023 | 0.84 | MAPT (0.69) | LMNAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27823198 | 0.83 | RECQL (0.70) | EPHX2PRMT6LMNAAOC3ERCC1 | |
| SCHEMBL30259900 | 0.83 | AOC3 (0.72) | LMNAAOC3KMT2A | |
| SCHEMBL24278725 | 0.79 | F3 (0.51) | — | |
| SCHEMBL29431795 | 0.79 | F3 (0.51) | — | |
| SCHEMBL951717 | 0.79 | ROCK2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |