Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218911 | 0.96 | TBXAS1 (0.55) | EPHX2PRMT6KMOBACE1MKNK1 | |
| SCHEMBL6027 | 0.85 | MKNK1 (0.58) | MKNK1MKNK2TBXAS1CYP2A6KMT2A | |
| SCHEMBL933474 | 0.85 | PRKCI (0.57) | PRMT6MKNK2 | |
| SCHEMBL5176875 | 0.84 | EPHX2 (0.55) | EPHX2PRMT6KMOBACE1MKNK1 | |
| SCHEMBL933853 | 0.83 | TBXAS1 (0.68) | TBXAS1RECQLCYP2A6KMT2A | |
| SCHEMBL3187079 | 0.82 | CYP2A6 (0.67) | EPHX2PRMT6KMOBACE1MKNK1 | |
| SCHEMBL27823198 | 0.80 | RECQL (0.70) | EPHX2PRMT6KMOBACE1MKNK1 | |
| SCHEMBL5218649 | 0.80 | TRPV1 (0.58) | EPHX2MEN1KMT2A | |
| SCHEMBL2183677 | 0.79 | AOC3 (0.43) | BACE1 | |
| SCHEMBL1139185 | 0.79 | EPHX2 (0.59) | EPHX2PRMT6KMOBACE1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |