Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934607 | 0.85 | EPHX2 (0.51) | PRMT6MKNK2 | |
| SCHEMBL933900 | 0.82 | CYP17A1 (0.51) | ROCK2CES1FAAHCHUKCYP17A1 | |
| SCHEMBL6037977 | 0.81 | MAPT (0.54) | PLA2G10PLA2G2ACES1FAAH | |
| SCHEMBL5218911 | 0.81 | TBXAS1 (0.55) | PRMT6MKNK2CES1FAAH | |
| SCHEMBL10287586 | 0.81 | PRKCI (0.59) | PRKCIPRMT6HRH3CYP17A1CYP3A4 | |
| SCHEMBL18772373 | 0.79 | FFAR1 (0.52) | PLA2G10PLA2G2A | |
| SCHEMBL952139 | 0.78 | CD74 (0.54) | PLA2G10PLA2G2A | |
| SCHEMBL1286084 | 0.78 | HRH1 (0.53) | HRH3CYP17A1 | |
| SCHEMBL951718 | 0.77 | ROCK2 (0.50) | ROCK2 | |
| SCHEMBL1138646 | 0.77 | PRKCI (0.73) | PRKCIPRMT6ABHD6MAP4K4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |