Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27633470 | 0.81 | SMN1; SMN2 (0.47) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9346174 | 0.73 | TUBB4A (0.52) | MAPTNPSR1POLBCYP2C9CES2 | |
| SCHEMBL10953514 | 0.71 | RAB9A (0.67) | MAPTCYP1A2L3MBTL1CES2CES1 | |
| SCHEMBL31342301 | 0.71 | AKR1C3 (0.50) | POLBALDH1A1KDM4ESRD5A2 | |
| SCHEMBL2434292 | 0.71 | NR4A1 (0.61) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9341973 | 0.71 | ALDH1A1 (0.78) | MAPTNPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5217869 | 0.70 | CYP1A2 (0.43) | MAPTPOLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL50462 | 0.69 | SRD5A2 (0.74) | MAPTL3MBTL1CES2CES1ALDH1A1 | |
| SCHEMBL9442387 | 0.69 | SRD5A2 (0.74) | MAPTL3MBTL1CES2CES1ALDH1A1 | |
| Alcohol SCHEMBL28353828 | 0.69 | SRD5A2 (0.61) | MAPTL3MBTL1CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318983-A | Fungicides and bactericides having broad spectrum activity to mycetes and Grampositive and Gramnegative bacteria | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1994-06-07 | — | — | US | disclosed |
| EP-0569575-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-11-18 | — | — | EP | disclosed |
| WO-1993011124-A1 | TRISUBSTITUTED PYRROLE DERIVATIVES HAVING ANTIFUNGINE ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS | APR APPLIED PHARMA RESEARCH S.A. (CH) | 1993-06-10 | — | — | WO | disclosed |