Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 9/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961989 | 0.82 | PTGS2 (0.76) | PTGS1PTGS2ALOX5POLB | |
| SCHEMBL8978636 | 0.76 | PTGS1 (0.40) | PTGS1PTGS2ALOX5MEN1KMT2A | |
| SCHEMBL8978826 | 0.75 | PTGS1 (0.43) | PTGS1PTGS2ALOX5MEN1KMT2A | |
| SCHEMBL9346192 | 0.75 | PTGS1 (0.43) | PTGS1PTGS2ALOX5MEN1KMT2A | |
| SCHEMBL8978838 | 0.75 | PTGS1 (0.43) | PTGS1PTGS2ALOX5MEN1KMT2A | |
| SCHEMBL8962192 | 0.73 | PTGS2 (0.78) | PTGS1PTGS2ALOX5POLB | |
| SCHEMBL8962137 | 0.73 | PTGS2 (0.78) | PTGS1PTGS2ALOX5POLB | |
| SCHEMBL8961992 | 0.69 | PTGS2 (1.00) | PTGS1PTGS2ALOX5POLB | |
| SCHEMBL8961923 | 0.69 | PTGS2 (0.68) | PTGS1PTGS2ALOX5 | |
| SCHEMBL8962093 | 0.69 | PTGS2 (0.68) | PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290800-A | Enzyme inhibitors | WARNER-LAMBERT COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| US-5143928-A | Inhibitors of cyclooxygenase and lipoxygenase | WARNER-LAMBERT COMPANY (US) | 1992-09-01 | — | — | US | disclosed |