Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7236617 | 0.89 | SLC13A5 (0.62) | SLC13A5LPAR1FFAR1MMEMMEL1 | |
| SCHEMBL3677264 | 0.82 | FFAR1 (0.66) | SLC13A5FFAR1MMEMMEL1PPARG | |
| SCHEMBL12646406 | 0.81 | SLC13A5 (0.56) | SLC13A5FFAR1MMEMMEL1PPARG | |
| SCHEMBL934360 | 0.81 | MME (0.45) | FFAR1MMEPPARGPPARAKMT2A | |
| SCHEMBL7357330 | 0.80 | MME (0.55) | MMEMMEL1HPGDLMNAKMT2A | |
| SCHEMBL29411612 | 0.78 | ALDH1A1 (0.62) | FFAR1MMEPPARGPPARARAB9A | |
| SCHEMBL6504790 | 0.77 | SLC13A5 (0.54) | SLC13A5MMEMMEL1PPARGPPARA | |
| SCHEMBL7446944 | 0.77 | SLC13A5 (0.55) | SLC13A5FFAR1MMEMMEL1PPARG | |
| SCHEMBL3467962 | 0.77 | PPARG (0.54) | SLC13A5LPAR1FFAR1MMEMMEL1 | |
| SCHEMBL2013598 | 0.77 | ICMT (0.42) | PPARGPPARAICMTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |