Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109610 | 0.82 | RARB (0.48) | MMEFFAR1FFAR4PPARGPPARA | |
| SCHEMBL29411612 | 0.81 | ALDH1A1 (0.62) | MMEFFAR1PPARGPPARARARB | |
| SCHEMBL1510067 | 0.81 | FFAR1 (0.66) | MMEFFAR1FFAR4 | |
| SCHEMBL934732 | 0.81 | SLC13A5 (0.55) | MMEFFAR1PPARGPPARAALDH1A1 | |
| SCHEMBL11262500 | 0.80 | FFAR1 (0.63) | FFAR1HDAC2HDAC1SMN1; SMN2HDAC3 | |
| SCHEMBL7350032 | 0.79 | LTB4R2 (0.52) | MMEMEN1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL4981917 | 0.78 | TDP1 (0.52) | MMECA12CA1CA2CA9 | |
| SCHEMBL12646475 | 0.77 | FFAR1 (0.49) | MMECA12CA9FFAR1FFAR4 | |
| SCHEMBL10900648 | 0.76 | HTR7 (0.67) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL661277 | 0.76 | PLAAT3 (0.51) | FFAR1HDAC2HDAC1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |