Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466555 | 0.91 | LPAR1 (0.50) | PPARGPPARASLC13A5LPAR1FFAR1 | |
| SCHEMBL3467371 | 0.84 | MMP3 (0.58) | GRIK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7918302 | 0.83 | MAPK1 (0.46) | PPARGSLC13A5FFAR1GRIK1PTGES | |
| SCHEMBL3467355 | 0.82 | GRIK1 (0.51) | GRIK1MME | |
| SCHEMBL1856418 | 0.82 | ALDH1A1 (0.56) | GRIK1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1861903 | 0.81 | GRIK1 (0.59) | FFAR1GRIK1MME | |
| SCHEMBL7446944 | 0.81 | SLC13A5 (0.55) | PPARGPPARASLC13A5FFAR1ITGA4 | |
| SCHEMBL7923945 | 0.81 | MMP2 (0.57) | PPARGPPARAFFAR1GRIK1MME | |
| SCHEMBL1860416 | 0.80 | GRIK1 (0.68) | PPARGPPARAGRIK1PTGESALOX5 | |
| SCHEMBL7236617 | 0.79 | SLC13A5 (0.62) | PPARGPPARASLC13A5LPAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |