Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467915 | 0.90 | APP (0.38) | EGLN1TYREPHX2ALDH1A1MAPT | |
| SCHEMBL9348191 | 0.73 | SCN5A (0.31) | — | |
| SCHEMBL9331303 | 0.71 | TOP1 (0.50) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9330012 | 0.71 | ALDH1A1 (0.47) | EGLN1EPHX2ALDH1A1KDM4ELMNA | |
| SCHEMBL5992305 | 0.71 | EGFR (0.56) | ALDH1A1MAPTMAPK1KDM4ELMNA | |
| SCHEMBL9332044 | 0.71 | ERCC1 (0.36) | ALDH1A1AURKAKDM4ELMNAHPGD | |
| SCHEMBL8082564 | 0.70 | MEN1 (0.49) | ALDH1A1MAPTMAPK1KDM4ELMNA | |
| SCHEMBL9795277 | 0.69 | HPGDS (0.49) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9658601 | 0.69 | TDP1 (0.42) | ALDH1A1MAPTAPPMAPK1KDM4E | |
| SCHEMBL5992310 | 0.68 | KMT2A (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |