Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075796 | 0.92 | GFER (0.46) | HPGDSLMNAALDH1A1HPGDESR1 | |
| SCHEMBL9331303 | 0.83 | TOP1 (0.50) | HPGDSALDH1A1HDAC6KDM4EGAA | |
| SCHEMBL8082564 | 0.79 | MEN1 (0.49) | HPGDSLMNAALDH1A1HPGDKDM4E | |
| SCHEMBL11532618 | 0.77 | ALDH1A1 (0.56) | HPGDSLMNANPC1ALDH1A1HPGD | |
| SCHEMBL3756762 | 0.77 | ALDH1A1 (0.73) | LMNANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL2919150 | 0.77 | ALDH1A1 (0.73) | LMNANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL3755011 | 0.77 | ALDH1A1 (0.73) | LMNANPC1ALDH1A1HPGDKDM4E | |
| SCHEMBL10546059 | 0.76 | GFER (0.47) | LMNAALDH1A1HPGDESR1ESR2 | |
| SCHEMBL9848415 | 0.75 | LMNA (0.53) | HPGDSLMNANPC1ALDH1A1HPGD | |
| SCHEMBL11700544 | 0.74 | MTNR1A (0.44) | ALDH1A1CTRB1KDM4EKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037975-A | Antibiotics | ELI LILLY AND COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-4939249-A | HEATING CEPHALOSPORIN 1,1-DIOXIDE IN SOLVENT WITH FREE RADICAL INITIATOR | ELI LILLY AND COMPANY (US) | 1990-07-03 | — | — | US | disclosed |