Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12697198 | 0.82 | RRM2 (0.46) | NPSR1MAPTKCNQ3KCNQ2HDAC1 | |
| SCHEMBL20037762 | 0.81 | MAPT (0.43) | NPSR1MAPTKCNQ3KCNQ2HDAC1 | |
| SCHEMBL25650053 | 0.81 | STK17A (0.42) | NPSR1MAPTKCNQ3KCNQ2HDAC1 | |
| SCHEMBL14197601 | 0.79 | RRM2 (0.48) | MAPTKCNQ3KCNQ2HDAC1HDAC6 | |
| SCHEMBL12788678 | 0.78 | SLC22A12 (0.41) | NPSR1MAPTKCNQ3KCNQ2HDAC1 | |
| SCHEMBL3632606 | 0.78 | ADRA2A (0.50) | NPSR1MAPTKCNQ3KCNQ2HDAC1 | |
| SCHEMBL23579386 | 0.77 | FDFT1 (0.41) | MAPTKDM4EMEN1KMT2AEGFR | |
| SCHEMBL29974870 | 0.77 | FDFT1 (0.41) | MAPTKDM4EMEN1KMT2AEGFR | |
| SCHEMBL18386498 | 0.77 | KCNH3 (0.48) | NPSR1SMN1; SMN2 | |
| SCHEMBL22278995 | 0.76 | NPSR1 (0.38) | NPSR1KCNQ3KCNQ2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1085204-C | The intermediates for preparation of 2-chloro-5-alkyl aminomethylpyridines | BAYER AG (DE) | 2002-05-22 | — | — | CN | disclosed |
| CN-1220989-A | The intermediates for preparation of 2-chloro-5-alkyl aminomethylpyridines | BAYER AG (DE) | 1999-06-30 | — | — | CN | disclosed |
| CN-1042934-C | Process for preparing 2-chloro-5-alkylaminomethylpyridines | BAYER AG (DE) | 1999-04-14 | — | — | CN | disclosed |
| EP-0609811-A1 | Process for preparing 2-chloro-5-aminomethyl-pyridine | KOEI CHEMICAL CO., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |
| CN-1075958-A | Process for preparing 2-chloro-5-alkylaminomethylpyridines | BAYER AG (DE) | 1993-09-08 | — | — | CN | disclosed |