Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12697198 | 0.82 | RRM2 (0.46) | KCNQ3KCNQ2HDAC1HDAC8HDAC6 | |
| SCHEMBL9347587 | 0.81 | NPSR1 (0.40) | KCNQ3KCNQ2HDAC1HDAC8HDAC6 | |
| SCHEMBL20037762 | 0.81 | MAPT (0.43) | STK17AKCNQ3KCNQ2CYP1A2CYP2C19 | |
| SCHEMBL1074469 | 0.80 | STK17A (0.40) | STK17AHDAC1ZAP70SYKMAPT | |
| SCHEMBL14197601 | 0.79 | RRM2 (0.48) | KCNQ3KCNQ2HDAC1HDAC8HDAC6 | |
| SCHEMBL12788678 | 0.78 | SLC22A12 (0.41) | KCNQ3KCNQ2HDAC1HDAC8HDAC6 | |
| SCHEMBL3632606 | 0.78 | ADRA2A (0.50) | KCNQ3KCNQ2HDAC1HDAC8HDAC6 | |
| SCHEMBL9220618 | 0.77 | STK17A (0.44) | STK17AKCNQ3KCNQ2MAPTGAA | |
| SCHEMBL4574251 | 0.77 | KMT2A (0.53) | HDAC1HDAC8HDAC6MAPTNPSR1 | |
| SCHEMBL18386498 | 0.77 | KCNH3 (0.48) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |