Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275930 | 1.00 | ALOX5 (0.46) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL1760592 | 0.86 | ESR2 (0.53) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL1535884 | 0.85 | BACE1 (0.54) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL949284 | 0.83 | BACE1 (0.52) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL29587494 | 0.81 | CRHBP (0.48) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL27957735 | 0.81 | PDE4B (0.44) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL1697210 | 0.81 | ALDH1A1 (0.54) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL29140551 | 0.81 | CRHBP (0.48) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL27557303 | 0.81 | HSD17B10 (0.50) | ALOX5BACE1PDE4BPDE4APDE4C | |
| SCHEMBL27485021 | 0.81 | KDM4E (0.46) | ALOX5BACE1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068597-C | Process for preparing 4 -aryl -piperidine derivatives | NOVO NORDISK AS (DK) | 2001-07-18 | — | — | CN | disclosed |
| CN-1184476-A | Process for preparing 4 -aryl -piperidine derivatives | NOVO NORDISK AS (DK) | 1998-06-10 | — | — | CN | disclosed |
| EP-0394822-B1 | Oxygen absorbent | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5180518-A | Food preservatives | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0394822-A1 | Oxygen absorbent | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-10-31 | — | — | EP | disclosed |