Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101449 | 1.00 | TDO2 (0.38) | TDO2FFAR2CELCYP11B2JAK2 | |
| SCHEMBL28948825 | 0.74 | TDO2 (0.39) | TDO2CELCYP11B2JAK2JAK1 | |
| SCHEMBL21306225 | 0.74 | HRH2 (0.33) | TDO2CYP11B2JAK2JAK1TYK2 | |
| SCHEMBL2355698 | 0.71 | CEL (0.37) | TDO2FFAR2CELCYP11B2JAK2 | |
| SCHEMBL6396174 | 0.70 | HRH2 (0.32) | ALDH1A1 | |
| SCHEMBL10456696 | 0.69 | FFAR2 (0.34) | TDO2FFAR2CYP11B2ALDH1A1NOTUM | |
| SCHEMBL11757350 | 0.65 | EPHX2 (0.37) | FFAR2JAK2JAK1JAK3 | |
| SCHEMBL10818372 | 0.64 | PDE4A (0.33) | TDO2CYP11B2ALDH1A1 | |
| SCHEMBL18167344 | 0.63 | TDO2 (0.40) | TDO2 | |
| SCHEMBL6040438 | 0.63 | TDO2 (0.32) | TDO2CEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414855-B2 | Multifunctional polyamides for protective coatings | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2019-09-17 | — | — | US | disclosed |
| EP-3143067-A1 | MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS | Huntsman Advanced Materials Americas LLC (US) | 2017-03-22 | — | — | EP | disclosed |
| US-20170051100-A1 | MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2017-02-23 | — | — | US | disclosed |
| WO-2015175583-A1 | MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2015-11-19 | — | — | WO | disclosed |
| US-5319004-A | Good water resistance | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5017675-A | Flexibility | HOECHST AG (DE) | 1991-05-21 | — | — | US | disclosed |