Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | JAK1 | P23458 | 3/20 | 0.31 |
| ▸ | TYK2 | P29597 | 3/20 | 0.31 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350412 | 1.00 | TDO2 (0.38) | TDO2FFAR2CELCYP11B2JAK2 | |
| SCHEMBL28948825 | 0.74 | TDO2 (0.39) | TDO2CELCYP11B2JAK2JAK1 | |
| SCHEMBL21306225 | 0.74 | HRH2 (0.33) | TDO2CYP11B2JAK2JAK1TYK2 | |
| SCHEMBL2355698 | 0.71 | CEL (0.37) | TDO2FFAR2CELCYP11B2JAK2 | |
| SCHEMBL6396174 | 0.70 | HRH2 (0.32) | ALDH1A1 | |
| SCHEMBL10456696 | 0.69 | FFAR2 (0.34) | TDO2FFAR2CYP11B2ALDH1A1NOTUM | |
| SCHEMBL11757350 | 0.65 | EPHX2 (0.37) | FFAR2JAK2JAK1JAK3 | |
| SCHEMBL10818372 | 0.64 | PDE4A (0.33) | TDO2CYP11B2ALDH1A1 | |
| SCHEMBL18167344 | 0.63 | TDO2 (0.40) | TDO2 | |
| SCHEMBL6040438 | 0.63 | TDO2 (0.32) | TDO2CEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999370-A | Multifunctional polyamides for protective coatings | 亨斯迈先进材料美国有限责任公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-2744605-B1 | COATINGS, MATERIALS AND PROCESSES FOR LEAD AND COPPER WATER SERVICE LINES | PIPE RESTORATION TECH LLC (US) | 2021-09-15 | — | — | EP | disclosed |
| US-10449569-B2 | Process for coating the interior surface of non-metallic pipes with metal valves and metal fittings | PIPE RESTORATION TECHNOLOGIES, LLC (US) | 2019-10-22 | — | — | US | disclosed |
| US-20190210064-A1 | PROCESS FOR COATING THE INTERIOR SURFACE OF NON-METALLIC PIPES WITH METAL VALVES AND METAL FITTINGS | PIPE RESTORATION TECH LLC (US) | 2019-07-11 | — | — | US | disclosed |
| US-10279375-B2 | Process for coating the interior surface of non-metallic pipes with metal valves and metal fittings | PIPE RESTORATION TECHNOLOGIES, LLC (US) | 2019-05-07 | — | — | US | disclosed |
| US-20180021808-A1 | Process for Coating the Interior Surface of Non-Metallic Pipes with Metal Valves and Metal Fittings | PIPE RESTORATION TECH LLC (US) | 2018-01-25 | — | — | US | disclosed |
| US-9764354-B2 | Process for coating the interior surface of underground pipes | PIPE RESTORATION TECHNOLOGIES, LLC (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170175944-A1 | Process for Coating the Interior Surface of Underground Pipes | PIPE RESTORATION TECH LLC (US) | 2017-06-22 | — | — | US | disclosed |
| EP-2974800-B1 | PROCESSES FOR LEAD AND METAL WATER SERVICE LINES | PIPE RESTORATION TECH LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| US-9611973-B2 | Process for coating the interior surface of water service lines | PIPE RESTORATION TECHNOLOGIES, LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-20050202257-A1 | Organo-functional polysiloxanes | SIGMAKALON SERVICES B.V. (NL) | 2005-09-15 | — | — | US | disclosed |
| US-20050148752-A1 | Amino-functional polysiloxanes and their use in coatings | SIGMAKALON SERVICES B.V. (NL) | 2005-07-07 | — | — | US | disclosed |
| EP-1526150-A1 | Anti-skid coating compositions | SigmaKalon Services B.V. (NL) | 2005-04-27 | — | — | EP | disclosed |
| EP-1504051-A1 | ORGANO-FUNCTIONAL POLYSILOXANES | SigmaKalon Services B.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| EP-1501884-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SigmaKalon Services B.V. (NL) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093352-A1 | AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003093350-A1 | ORGANO-FUNCTIONAL POLYSILOXANES | SIGMAKALON SERVICES B.V. (NL) | 2003-11-13 | — | — | WO | disclosed |
| EP-1361245-A1 | Amino-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-12 | — | — | EP | disclosed |
| EP-1359182-A1 | Organo-functional polysiloxanes | SigmaKalon Group B.V. (NL) | 2003-11-05 | — | — | EP | disclosed |
| EP-1314716-A1 | Amine phenolic compounds and their use as hardener and/or accelerators in epoxy coatings | SIGMA COATINGS B.V. (NL) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050202257-A1 | Organo-functional polysiloxanes | H1-3, HAO2, LPO | TDO2 57/4885FFAR2 1435/4885CEL 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.