Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL9346943 | 0.81 | THRB (0.60) | THRBMMP2ITGB3ITGA2BCPB2 | |
| Lysine SCHEMBL11276606 | 0.79 | THRB (0.58) | THRBMMP2ITGB3ITGA2BCPB2 | |
| SCHEMBL1191631 | 0.77 | GSR (0.53) | CPB2GSR | |
| SCHEMBL5010331 | 0.77 | GSR (0.53) | CPB2GSR | |
| SCHEMBL27811069 | 0.76 | TDP1 (0.51) | PTGS2EPHX1ALOX5CYP4F2CYP4A11 | |
| SCHEMBL8836895 | 0.75 | GSR (0.52) | CPB2GSR | |
| SCHEMBL8950857 | 0.75 | GSR (0.52) | CPB2GSR | |
| Water SCHEMBL5501375 | 0.75 | GSR (0.52) | CPB2GSR | |
| SCHEMBL8759024 | 0.75 | GSR (0.52) | THRBCPB2GSR | |
| SCHEMBL1065054 | 0.75 | GSR (0.52) | THRBCPB2GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253083-B1 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LISAPHARMA SPA (IT) | 1994-08-31 | — | — | EP | claimed |
| US-4755533-A | Topical vaginal use of lysine p-isobutylphenylpropionate in anti-inflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA SPA (IT) | 1988-07-05 | — | — | US | claimed |
| EP-0253083-A2 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA S.P.A. (IT) | 1988-01-20 | — | — | EP | claimed |
| EP-0253083-B1 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LISAPHARMA SPA (IT) | 1994-08-31 | — | — | EP | disclosed |
| EP-0253083-B1 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LISAPHARMA SPA (IT) | 1994-08-31 | — | — | EP | disclosed |
| US-4755533-A | Topical vaginal use of lysine p-isobutylphenylpropionate in anti-inflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA SPA (IT) | 1988-07-05 | — | — | US | disclosed |
| US-4755533-A | Topical vaginal use of lysine p-isobutylphenylpropionate in anti-inflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA SPA (IT) | 1988-07-05 | — | — | US | disclosed |
| US-4755533-A | Topical vaginal use of lysine p-isobutylphenylpropionate in anti-inflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA SPA (IT) | 1988-07-05 | — | — | US | disclosed |
| EP-0253083-A2 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA S.P.A. (IT) | 1988-01-20 | — | — | EP | disclosed |
| EP-0253083-A2 | Topical vaginal use of lysine p-isobutylphenylpropionate in antiinflammatory treatment | LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA S.P.A. (IT) | 1988-01-20 | — | — | EP | disclosed |