SCHEMBL9350754

SCHEMBL9350754

C=CC(=O)OC1CC(C)(C)N(OC)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.36
ESR1 P03372 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GAA P10253 2/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25701767 0.87 TSHR (0.43) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL9400301 0.84 TSHR (0.55) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL69507 0.83 TSHR (0.33) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL3191892 0.83 TSHR (0.33) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL1053833 0.83 GAA (0.44) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL7795589 0.83 ALDH1A1 (0.42) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL25701766 0.81 TSHR (0.35) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL1685817 0.81 TSHR (0.33) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL8850033 0.81 TSHR (0.33) TSHRKMT2AALDH1A1ESR1HSD17B10
Ethylene SCHEMBL11193217 0.81 TSHR (0.33) TSHRKMT2AALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US claimed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
US-20240002563-A1 CURABLE POLYMER COMPOSITION Kraton Corporation (US) 2024-01-04 US disclosed
EP-4299645-A1 CURABLE POLYMER COMPOSITION Kraton Polymers Nederland B.V. (NL) 2024-01-03 EP disclosed
US-11248114-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2022-02-15 US disclosed
WO-2017166762-A1 CROSSLINKABLE POLYMERIC COMPOSITIONS WITH METHYL-RADICAL SCAVENGERS AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-05 WO disclosed
WO-2017166105-A1 CROSSLINKABLE POLYMERIC COMPOSITIONS WITH METHYL-RADICAL SCAVENGERS AND ARTICLES MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-05 WO disclosed
US-20130059952-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS BASF SE (DE) 2013-03-07 US disclosed
US-20130059952-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS BASF SE (DE) 2013-03-07 US disclosed
WO-2011086114-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS BASF SE (DE) 2011-07-21 WO disclosed
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5077340-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US disclosed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US disclosed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059952-A1 PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS PFAS, PHOSPHO1, PIK3CA TSHR 2762/4885KMT2A 800/4885ALDH1A1 2401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.