SCHEMBL9350803

SCHEMBL9350803

CC1(C)CC(N(C(=O)CCCCCCCCC(=O)N(C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)C2CC(C)(C)N(OC3CCCCC3)C(C)(C)C2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.38
KDM5A P29375 2/20 0.32
PHF8 Q9UPP1 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32
KDM4C Q9H3R0 1/20 0.32
KDM4A O75164 1/20 0.32
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351026 0.93 NAAA (0.31) NAAA
SCHEMBL9350975 0.83 TSHR (0.33)
SCHEMBL698203 0.78 NAAA (0.56) NAAASMN1; SMN2
SCHEMBL10467609 0.78 NAAA (0.56) NAAASMN1; SMN2
SCHEMBL9743615 0.78 NAAA (0.56) NAAASMN1; SMN2
SCHEMBL30894534 0.78 NAAA (0.56) NAAASMN1; SMN2
SCHEMBL7478446 0.78 NAAA (0.31) NAAA
SCHEMBL9273053 0.77 TSHR (0.31)
SCHEMBL9350774 0.77 TRPM8 (0.30)
SCHEMBL30894533 0.77 NAAA (0.55) NAAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 US claimed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed