SCHEMBL9350774

SCHEMBL9350774

C=CC(=O)N(C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1)C1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25701843 0.89
SCHEMBL9350975 0.84 TSHR (0.33)
SCHEMBL9351026 0.81 NAAA (0.31)
SCHEMBL9273053 0.79 TSHR (0.31)
SCHEMBL9350731 0.78 TSHR (0.34)
SCHEMBL9350803 0.77 NAAA (0.38)
SCHEMBL9350745 0.76 EPHX2 (0.34)
SCHEMBL25701841 0.75 ALDH1A1 (0.40)
SCHEMBL25701834 0.75
SCHEMBL6174558 0.72 APLNR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5077340-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US disclosed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US disclosed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed