Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350956 | 1.00 | PTP4A1 (0.75) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8848401 | 0.86 | FTO (0.69) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8848400 | 0.86 | FTO (0.69) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16160390 | 0.86 | FTO (0.69) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9218611 | 0.86 | DNM1 (0.80) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17545166 | 0.86 | DNM1 (0.80) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9218618 | 0.86 | DNM1 (0.80) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL23530140 | 0.85 | ALDH1A1 (0.75) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2211505 | 0.85 | ALDH1A1 (0.75) | PTP4A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19677657 | 0.84 | PTP4A1 (0.68) | PTP4A1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339671-B1 | Derivative of caffeic acid and pharmaceutical composition containing the same | SUNTORY LTD (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5063243-A | Arteriosclerosis treatment | SUNTORY, LTD. (JP) | 1991-11-05 | — | — | US | disclosed |