Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931146 | 0.87 | HIF1A (0.48) | ADRA1ATAAR1HTR2AHTR2CIDO1 | |
| SCHEMBL9229255 | 0.79 | APLNR (0.63) | HTR2AHTR2CMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8931145 | 0.78 | APLNR (0.61) | HTR2AHTR2CMEN1KMT2AHSD17B10 | |
| SCHEMBL29633027 | 0.77 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL29633101 | 0.77 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL17287296 | 0.77 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL8931156 | 0.74 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL3350055 | 0.73 | CAPN1 (0.50) | ADRA1ATAAR1HTR2AHTR2CMTNR1A | |
| SCHEMBL10032817 | 0.73 | HTR2A (0.62) | HTR2AHTR2CMEN1KMT2A | |
| SCHEMBL30277352 | 0.73 | MPO (0.75) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613458-A1 | ACYCLIC ETHYLENEDIAMINE DERIVATIVES AS SUBSTANCE P RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-09-07 | — | — | EP | claimed |