SCHEMBL17287296

SCHEMBL17287296

COc1ccc(OC)c(CCNCc2ccccc2OC)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 0.67
HTR2C P28335 5/20 0.67
HRH1 P35367 2/20 0.67
OPRM1 P35372 2/20 0.67
OPRK1 P41145 2/20 0.67
HTR2B P41595 2/20 0.67
HTR6 P50406 2/20 0.67
MPO P05164 1/20 0.61
CHRM2 P08172 9/20 0.59
GRIN1 Q05586 4/20 0.59
GRIN2A Q12879 4/20 0.59
BCHE P06276 4/20 0.59
ACHE P22303 4/20 0.59
CHRM4 P08173 2/20 0.59
CHRM5 P08912 2/20 0.59
CHRM1 P11229 2/20 0.59
CHRM3 P20309 2/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633101 1.00 HTR2A (0.67) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL29633027 1.00 HTR2A (0.67) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL30277352 0.89 MPO (0.75) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL10032817 0.84 HTR2A (0.62) HTR2AHTR2CBCHE
SCHEMBL24733397 0.84 HTR2A (0.59) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL31218188 0.84 HTR2A (0.59) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL31218191 0.83 HTR2A (0.58) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL24733369 0.83 HTR2A (0.58) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL24733374 0.83 HTR2A (0.58) HTR2AHTR2CHRH1OPRM1OPRK1
SCHEMBL19171129 0.82 HTR2A (0.75) HTR2AHTR2CHRH1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2950104-B1 IMMUNOASSAY FOR COMPOUNDS OF THE NBOME FAMILY RANDOX LABORATORIES LTD (GB) 2018-08-08 EP claimed
US-9720005-B2 Immunoassay for compounds of the NBOMe family RANDOX LABORATORIES LIMITED (GB) 2017-08-01 US claimed
EP-3841085-B1 NBOME TEST UNIV SYDNEY TECHNOLOGY (AU) 2026-05-06 EP disclosed
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US disclosed
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME KULEON LLC (US) 2026-04-02 US disclosed
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-10 US disclosed
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same Park City Bio, LLC (US) 2026-03-03 US disclosed
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same Park City Bio, LLC (US) 2025-12-11 US disclosed
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS KULEON LLC (US) 2025-11-06 US disclosed
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2025-09-18 US disclosed
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-25 US disclosed
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2021-11-11 US disclosed
EP-3841085-A1 NBOME TEST University Of Technology Sydney (AU) 2021-06-30 EP disclosed
US-20210190766-A1 NBOMe Test UNIVERSITY OF TECHNOLOGY SYDNEY (AU) 2021-06-24 US disclosed
US-20210190766-A1 NBOMe Test UNIVERSITY OF TECHNOLOGY SYDNEY (AU) 2021-06-24 US disclosed
WO-2020037372-A1 NBOME TEST UNIVERSITY OF TECHNOLOGY SYDNEY (AU) 2020-02-27 WO disclosed
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CAAMTECH, INC. 2019-05-16 US disclosed
EP-2950104-B1 IMMUNOASSAY FOR COMPOUNDS OF THE NBOME FAMILY RANDOX LABORATORIES LTD (GB) 2018-08-08 EP disclosed
EP-2950104-A1 IMMUNOASSAY FOR COMPOUNDS OF THE NBOME FAMILY Randox Laboratories Ltd. (GB) 2015-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142851-A1 COMPOSITIONS COMPRISING A PSILOCYBIN DERIVATIVE AND A CANNABINOID CNR1, CNR2, HTR5A HTR2A 6/4885HTR2C 8/4885HRH1 1378/4885
US-20250376436-A1 Selective Serotonin Receptor Modulators and Methods of Making and Using the Same HTR1A, HTR4, HTR5A HTR2A 8/4885HTR2C 7/4885HRH1 341/4885
US-20260092034-A1 7-AZAINDOLE ANALOGS AND METHODS OF TREATING NEUROLOGICAL DISORDERS USING THE SAME HTR2C, HTR7, HTR6 HTR2A 6/4885HTR2C 1/4885HRH1 191/4885
US-20250289817-A1 SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME HTR5A, HTR1A, HTR3A HTR2A 5/4885HTR2C 11/4885HRH1 326/4885
US-20210346346-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885HTR2C 11/4885HRH1 103/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A HTR2A 8/4885HTR2C 2/4885HRH1 341/4885
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND ADRA2C, ADRB3, ADRA2B HTR2A 19/4885HTR2C 12/4885HRH1 677/4885
US-20250340513-A1 NEUROPLASTOGENS AND NON-HALLUCINOGENIC SEROTONIN 5-HT2A/2C RECEPTOR MODULATORS HTR2A, HTR2C, HTR3A HTR2A 1/4885HTR2C 2/4885HRH1 353/4885
US-20210361679-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND HTR3A, HTR2A, HTR5A HTR2A 2/4885HTR2C 11/4885HRH1 103/4885
US-12570602-B2 Selective serotonin receptor modulators and methods of making and using the same HTR1D, HTR1A, HTR4 HTR2A 14/4885HTR2C 6/4885HRH1 251/4885
US-12564560-B1 Selective serotonin receptor modulators and methods of making and using the same HTR5A, HTR1A, HTR1D HTR2A 16/4885HTR2C 7/4885HRH1 1015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.