Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27779234 | 0.84 | CDK5 (0.50) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL19138009 | 0.82 | HTT (0.46) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL14917460 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL27434327 | 0.81 | GRM5 (0.43) | GRM5 | |
| SCHEMBL27332910 | 0.80 | HTT (0.59) | MEN1KMT2AALDH1A1GRM6SMN1; SMN2 | |
| SCHEMBL368305 | 0.80 | DHODH (0.47) | LMNAHSD17B10HTT | |
| SCHEMBL27610033 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL31184792 | 0.76 | KDM4E (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8325905 | 0.76 | L3MBTL1 (0.46) | ALDH1A1LMNAHPGDTP53SMN1; SMN2 | |
| SCHEMBL27537308 | 0.75 | MAPT (0.50) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350755-A | Treatment of psoriasis or eczema with naphthyridine derivative | SCHERING CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| US-4740511-A | ANTIALLERGENS, ANTIINFLAMMATORY, ANTIULCER AGENTS | SCHERING CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| US-4628055-A | ASTHMA, BRONCHITIS, 1,5,8-AZANAPHTHYRIDINES | SCHERING CORPORATION (US) | 1986-12-09 | — | — | US | disclosed |
| US-4492702-A | ATIALLERGENS, LUNG DISEASES | SCHERING CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |