Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12986139 | 0.83 | LMNA (0.42) | FFAR4AURKAMAPK1LMNAMAPT | |
| SCHEMBL933965 | 0.81 | PTPRZ1 (0.49) | MAPK1LMNAHTTFAAHCES1 | |
| SCHEMBL31173722 | 0.79 | PTPRZ1 (0.48) | FFAR4AURKAMAPK1LMNAMAPT | |
| SCHEMBL17288972 | 0.78 | FFAR4 (0.40) | FFAR4MAPK1LMNAMAPTTSHR | |
| SCHEMBL4309679 | 0.77 | TAAR1 (0.60) | FFAR4AURKAEPHX1HDAC1HDAC8 | |
| SCHEMBL2646892 | 0.75 | NR1H4 (0.51) | FFAR4MAPK1LMNAMAPTTSHR | |
| SCHEMBL2090292 | 0.74 | TAAR1 (0.56) | SLC6A3 | |
| SCHEMBL13064250 | 0.74 | CETP (0.40) | FFAR4UBE2MDCUN1D1SMN1; SMN2CETP | |
| SCHEMBL17288832 | 0.74 | FFAR4 (0.39) | FFAR4MAPK1LMNAMAPTTSHR | |
| SCHEMBL935243 | 0.74 | EPHX1 (0.44) | FFAR4MAPK1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |