Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.36 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933962 | 0.82 | PTPRZ1 (0.47) | EPHX1LMNAHTT | |
| SCHEMBL11547646 | 0.82 | HTR2A (0.58) | HTR2AHTR2CHTR2BCETP | |
| Hydrochloric Acid SCHEMBL11546088 | 0.81 | HTR2A (0.57) | HTR2AHTR2CHTR2BCETP | |
| SCHEMBL17449716 | 0.81 | HTR2A (0.44) | HTR2AHTR2CHTR2BCETPFFAR4 | |
| SCHEMBL15881786 | 0.78 | HTR2A (0.67) | EPHX1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL27274983 | 0.78 | HTR2A (0.67) | EPHX1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL12986139 | 0.78 | LMNA (0.42) | EPHX1CETPFFAR4UBE2MDCUN1D1 | |
| SCHEMBL27466730 | 0.77 | UBE2M (0.40) | EPHX1CETPFFAR4UBE2MDCUN1D1 | |
| Hydrochloric Acid SCHEMBL22188668 | 0.76 | ALDH1A1 (0.46) | HTR2AHTR2CHTR2BCETPFFAR4 | |
| SCHEMBL9989813 | 0.76 | SLC1A1 (0.55) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |