Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935246 | 0.81 | FFAR4 (0.45) | PTPRZ1KIF11FAAHLMNAHTT | |
| SCHEMBL9108524 | 0.81 | PTPRZ1 (0.61) | PTPRZ1PTPN1KIF11ALDH1A1KDM4E | |
| SCHEMBL10655803 | 0.78 | ALDH1A1 (0.52) | PTPRZ1PTPN1KIF11ALDH1A1KDM4E | |
| SCHEMBL6001747 | 0.78 | PTPRZ1 (0.65) | PTPRZ1PTPN1KIF11ALDH1A1KDM4E | |
| SCHEMBL934147 | 0.77 | HDAC1 (0.57) | PTPN1PTPN2PTPN6PTPN11HDAC3 | |
| Hydrochloric Acid SCHEMBL30882461 | 0.76 | HDAC1 (0.55) | PTPN1PTPN2PTPN6PTPN11HDAC1 | |
| SCHEMBL27597569 | 0.75 | PTPRZ1 (0.53) | PTPRZ1PTPN1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5544527 | 0.75 | PTPRZ1 (0.53) | PTPRZ1PTPN1KIF11ALDH1A1KDM4E | |
| SCHEMBL658360 | 0.74 | LMNA (0.54) | LMNA | |
| SCHEMBL3630994 | 0.74 | PTPRZ1 (0.57) | PTPRZ1PTPN1KIF11ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |