Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352481 | 0.79 | ALDH1A1 (0.41) | RAB9AALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL9355880 | 0.77 | MMP2 (0.32) | MMP2MMP9 | |
| SCHEMBL9355864 | 0.76 | FABP5 (0.39) | CASP3KMT2AEPHX2 | |
| SCHEMBL9356273 | 0.76 | ELANE (0.42) | MAPTL3MBTL1MMP2MMP9TDP1 | |
| SCHEMBL8517516 | 0.75 | KMT2A (0.43) | MAPTL3MBTL1ALDH1A1MMP1MMP9 | |
| SCHEMBL9351931 | 0.75 | CYP3A4 (0.34) | RAB9AMAPTALDH1A1MMP1MMP2 | |
| SCHEMBL9355644 | 0.74 | ALDH1A1 (0.48) | MAOAMAOBRAB9AMAPTNR4A2 | |
| SCHEMBL9646440 | 0.73 | KMT2A (0.50) | MAOBNR4A2L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL9619081 | 0.73 | MAPT (0.37) | RAB9AMAPTALDH1A1HTTPKM | |
| SCHEMBL9442127 | 0.72 | ELANE (0.38) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406567-B1 | Process for the production of sulfonium compounds and novel methylthiophenol derivatives | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5149857-A | Reacting alkylthiophenyl carbonates with dialkyl sulfates | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-09-22 | — | — | US | disclosed |