Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576286 | 0.89 | ELANE (0.47) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9619082 | 0.88 | MAPT (0.40) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9442120 | 0.87 | PKM (0.39) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9487566 | 0.84 | THRB (0.45) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9356342 | 0.82 | ELANE (0.53) | MAPTPOLBPKMKMT2AELANE | |
| Sulfuric Acid SCHEMBL5576288 | 0.79 | MAPT (0.38) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL5576290 | 0.79 | ELANE (0.46) | MAPTPOLBPKMKMT2ALMNA | |
| SCHEMBL9356273 | 0.78 | ELANE (0.42) | MAPTKMT2ALMNAELANESMN1; SMN2 | |
| SCHEMBL9355880 | 0.77 | MMP2 (0.32) | ELANE | |
| SCHEMBL9442127 | 0.77 | ELANE (0.38) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4360865-A | — | — | None | — | — | JP | disclosed |
| JP-H04360865-A | SULFONIUM COMPOUND | SANSHIN CHEM IND CO LTD | 1992-12-14 | — | — | JP | disclosed |