SCHEMBL935295

SCHEMBL935295

O=C(O)c1ccccc1C1=C2C=CC(=N2)C(c2ccccc2C(=O)O)=C2C=CC(=N2)C(c2ccccc2C(=O)O)=C2C=CC(=N2)C(c2ccccc2C(=O)O)=C2C=CC1=N2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.44
▸ FABP4 P15090 1/20 0.44
▸ FABP5 Q01469 1/20 0.44
▸ ALDH1A1 P00352 6/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ MYC P01106 1/20 0.42
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ ALOX12 P18054 1/20 0.41
▸ KDM4E B2RXH2 5/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ USP2 O75604 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ HNF4A P41235 1/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9391411 0.87 KMT2A (0.48) FABP3FABP4FABP5ALDH1A1GAA
SCHEMBL10679197 0.78 CSNK2A1 (0.45) ALDH1A1KDM4ECA12CA1CA2
SCHEMBL10681393 0.77 KDM4E (0.44) FABP3FABP4ALDH1A1KDM4EHPGD
SCHEMBL2534345 0.77 AKR1B1 (0.46) ALDH1A1CYP2C9KDM4EMAPT
SCHEMBL30028907 0.72 ALDH1A1 (0.72) ALDH1A1ALOX15GAAMYCCYP3A4
SCHEMBL36145 0.72 ALDH1A1 (0.72) ALDH1A1ALOX15GAAMYCCYP3A4
SCHEMBL25394857 0.71 NPC1 (0.47) ALDH1A1GAAKDM4ERAB9ATSHR
SCHEMBL25395879 0.71 NPC1 (0.47) ALDH1A1GAAKDM4ERAB9ATSHR
SCHEMBL483513 0.71 NPC1 (0.47) ALDH1A1GAAKDM4ERAB9ATSHR
SCHEMBL9404581 0.71 HPGD (0.47) ALDH1A1ALOX15GAACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975038-B2 Method for determining presence of carcinomic cells with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOAFFINITY TECHNOLOGIES, INC. (US) 2015-03-10 — — US claimed
EP-2372361-B1 Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA INC (US) 2014-08-06 — — EP claimed
US-20140162287-A1 Method for Prognosing Response to Cancer Therapy with 5, 10, 15, 20-Tetrakis (Carboxyphenyl) Porphine BIOMODA, INC. 2014-06-12 — — US claimed
EP-1364044-B1 COMPOSITIONS AND METHODS FOR DETECTING PRE-CANCEROUS CONDITIONS IN CELL AND TISSUE SAMPLES USING 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE BIOMODA INC (US) 2012-01-11 — — EP claimed
US-7960138-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2011-06-14 — — US claimed
US-7384764-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2008-06-10 — — US claimed
WO-2004041828-A1 METHOD OF USING A PORPHYRIN-LIKE MOLECULE CONJUGATED WITH AN ANTI-CANCER DRUG FOR THE TREATMENT OF CANCER HAN IN SUK (US) 2004-05-21 — — WO claimed
US-20020155999-A1 Method of using a porphyrin-like molecule conjugated with an anti-cancer drug for the treatment of cancer HAN IN SUK (US) 2002-10-24 — — US claimed
US-8975038-B2 Method for determining presence of carcinomic cells with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOAFFINITY TECHNOLOGIES, INC. (US) 2015-03-10 — — US disclosed
US-20140162287-A1 Method for Prognosing Response to Cancer Therapy with 5, 10, 15, 20-Tetrakis (Carboxyphenyl) Porphine BIOMODA, INC. 2014-06-12 — — US disclosed
EP-1364044-B1 COMPOSITIONS AND METHODS FOR DETECTING PRE-CANCEROUS CONDITIONS IN CELL AND TISSUE SAMPLES USING 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE BIOMODA INC (US) 2012-01-11 — — EP disclosed
EP-1364044-B1 COMPOSITIONS AND METHODS FOR DETECTING PRE-CANCEROUS CONDITIONS IN CELL AND TISSUE SAMPLES USING 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE BIOMODA INC (US) 2012-01-11 — — EP disclosed
EP-2372361-A1 Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine Biomoda, Inc. (US) 2011-10-05 — — EP disclosed
EP-2372361-A1 Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine Biomoda, Inc. (US) 2011-10-05 — — EP disclosed
US-7384764-B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine BIOMODA, INC. (US) 2008-06-10 — — US disclosed
US-20050233410-A1 Detecting cancerous and precancerous cells; obtain tissue sample, incubate wih tetrakis dyes, rince and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. 2005-10-20 — — US disclosed
US-20050233410-A1 Detecting cancerous and precancerous cells; obtain tissue sample, incubate wih tetrakis dyes, rince and remove unbound dye, detect fluorescence, fuorescence indicates cancerous or precancerous cells BIOMODA, INC. 2005-10-20 — — US disclosed
CN-1545557-A Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine �ݰ�Ī�﹫˾ 2004-11-10 — — CN disclosed
US-20020155999-A1 Method of using a porphyrin-like molecule conjugated with an anti-cancer drug for the treatment of cancer HAN IN SUK (US) 2002-10-24 — — US disclosed
US-5162231-A Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung LOS ALAMOS NATIONAL SECURITY, LLC 1992-11-10 — — US disclosed
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