Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 7/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679197 | 0.92 | CSNK2A1 (0.45) | KDM4EALDH1A1HSD17B10DHODHCSNK2A1 | |
| SCHEMBL9391411 | 0.86 | KMT2A (0.48) | KDM4EALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL28725358 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL935295 | 0.77 | FABP3 (0.44) | KDM4EALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL3912294 | 0.77 | NPC1 (0.43) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3913647 | 0.77 | NPC1 (0.43) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3733709 | 0.75 | HDAC7 (0.60) | KDM4EALDH1A1HSD17B10FABP3FABP4 | |
| SCHEMBL1977054 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL25395879 | 0.73 | NPC1 (0.47) | KDM4EALDH1A1CSNK2A1LDHAHPGD | |
| SCHEMBL25394857 | 0.73 | NPC1 (0.47) | KDM4EALDH1A1CSNK2A1LDHAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-05 | — | — | US | disclosed |
| EP-3386986-B1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | UNIV HONG KONG (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-08 | — | — | US | disclosed |
| US-4783529-A | Rapid synthesis of radiolabeled porphyrin complexes for medical application | RESEARCH CORPORATION TECHNOLOGIES (US) | 1988-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | HCCS, PPOX, LIG3 | KDM4E 4181/4885ALDH1A1 1068/4885HSD17B10 1867/4885 |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | HCCS, PPOX, LIG3 | KDM4E 4181/4885ALDH1A1 1068/4885HSD17B10 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.