Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681393 | 0.92 | KDM4E (0.44) | CSNK2A1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9391411 | 0.79 | KMT2A (0.48) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL935295 | 0.78 | FABP3 (0.44) | ALDH1A1POLBKDM4EHSD17B10CA9 | |
| SCHEMBL4621112 | 0.76 | CSNK2A1 (0.65) | CSNK2A1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL1977054 | 0.71 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL18116578 | 0.70 | CSNK2A1 (0.57) | CSNK2A1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL6495696 | 0.70 | HSD17B10 (0.58) | CSNK2A1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL223101 | 0.68 | CSNK2A1 (0.65) | CSNK2A1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31517191 | 0.68 | CSNK2A1 (0.54) | CSNK2A1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3733709 | 0.68 | HDAC7 (0.60) | CSNK2A1ALDH1A1POLBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-05 | — | — | US | disclosed |
| EP-3386986-B1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | UNIV HONG KONG (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-08 | — | — | US | disclosed |
| US-4783529-A | Rapid synthesis of radiolabeled porphyrin complexes for medical application | RESEARCH CORPORATION TECHNOLOGIES (US) | 1988-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | HCCS, PPOX, LIG3 | CSNK2A1 3988/4885MEN1 3439/4885KMT2A 4420/4885 |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | HCCS, PPOX, LIG3 | CSNK2A1 3988/4885MEN1 3439/4885KMT2A 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.