Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353293 | 0.95 | SLC6A3 (0.45) | MEN1KMT2ALMNAKCNH2SLC6A3 | |
| SCHEMBL1802065 | 0.82 | CYP3A4 (0.52) | MEN1KMT2ALMNAKCNH2SLC6A3 | |
| Hydrochloric Acid SCHEMBL7654483 | 0.80 | CYP3A4 (0.50) | MEN1KMT2ALMNAKCNH2SLC6A3 | |
| Carbamic Acid SCHEMBL17460309 | 0.73 | GAA (0.47) | MEN1KMT2ALMNANPSR1KCNH2 | |
| SCHEMBL10339412 | 0.72 | ACHE (0.43) | IDO1TDO2LMNANPSR1ACHE | |
| SCHEMBL8645362 | 0.70 | LMNA (0.81) | MEN1KMT2ALMNANPSR1KCNH2 | |
| SCHEMBL5169785 | 0.69 | HRH3 (0.46) | MEN1KMT2ALMNAACHE | |
| SCHEMBL14280201 | 0.69 | ACHE (0.71) | MEN1KMT2AACHE | |
| SCHEMBL8938188 | 0.69 | CHRNA7 (0.62) | MEN1KMT2ALMNANPSR1KCNH2 | |
| SCHEMBL8938184 | 0.69 | CHRNA7 (0.62) | MEN1KMT2ALMNANPSR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5410046-A | Selective muscarinic receptor antagonists | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0350309-B1 | PIPERIDINE DERIVATIVES | Pfizer Limited (GB) | 1992-11-11 | — | — | EP | disclosed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0350309-A1 | Piperidine derivatives | Pfizer Limited (GB) | 1990-01-10 | — | — | EP | disclosed |