Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802065 | 0.82 | CYP3A4 (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL7654483 | 0.80 | CYP3A4 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL28042294 | 0.79 | CYP2D6 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL7480934 | 0.77 | CYP2D6 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL9353293 | 0.77 | SLC6A3 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL29424742 | 0.76 | CYP2D6 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| Carbamic Acid SCHEMBL17460309 | 0.73 | GAA (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL8938188 | 0.73 | CHRNA7 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL8938184 | 0.73 | CHRNA7 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 | |
| SCHEMBL6929865 | 0.70 | LMNA (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACION IMDEA NANOCIENCIA (ES) | 2016-03-17 | — | — | US | claimed |
| EP-2992002-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | Fundación Imdea Nanociencia (ES) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177533-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACIÓN IMDEA NANOCIENCIA (ES) | 2014-11-06 | — | — | WO | claimed |
| EP-2799443-A1 | Modified solid support for the synthesis of oligonucleotides | Fundación Imdea Nanociencia (ES) | 2014-11-05 | — | — | EP | claimed |
| US-7135564-B1 | Reusable solid support for oligonucleotide synthesis | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2006-11-14 | — | — | US | claimed |
| EP-1091972-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2001-04-18 | — | — | EP | claimed |
| WO-2000001711-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-13 | — | — | WO | claimed |
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACION IMDEA NANOCIENCIA (ES) | 2016-03-17 | — | — | US | disclosed |
| EP-2992002-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | Fundación Imdea Nanociencia (ES) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177533-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | FUNDACIÓN IMDEA NANOCIENCIA (ES) | 2014-11-06 | — | — | WO | disclosed |
| EP-2799443-A1 | Modified solid support for the synthesis of oligonucleotides | Fundación Imdea Nanociencia (ES) | 2014-11-05 | — | — | EP | disclosed |
| US-7135564-B1 | Reusable solid support for oligonucleotide synthesis | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2006-11-14 | — | — | US | disclosed |
| EP-0877751-B1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIV TECHNOLOGIES INT (CA) | 2003-10-15 | — | — | EP | disclosed |
| US-6043353-A | FOR SOLID PHASE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL, INC. (CA) | 2000-03-28 | — | — | US | disclosed |
| US-6015895-A | REACTING A LINKER COMPOUND WITH A HYDROXY GROUP OF A NUCLEOSIDE AND A SOLID SUPPORT CAPABLE OF ESTERIFICATION; LINKER IS STABILE AGAINST SPONTANEOUS HYDROLYSIS AND EASILY CLEAVED WHEN NECESSARY | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-18 | — | — | US | disclosed |
| WO-2000001711-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 2000-01-13 | — | — | WO | disclosed |
| EP-0877751-A1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1998-11-18 | — | — | EP | disclosed |
| EP-0876390-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR USE THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997023497-A1 | LINKER ARM FOR SOLID SUPPORT OLIGONUCLEOTIDE SYNTHESIS AND PROCESS FOR PRODUCTION THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1997-07-03 | — | — | WO | disclosed |
| WO-1997023496-A1 | REUSABLE SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR USE THEREOF | UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075680-A1 | MODIFIED SOLID SUPPORT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | POLR2H, POLRMT, POLR2E | CYP1A2 4793/4885CYP3A4 4218/4885CYP2D6 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.