Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936239 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1GPR84ITGB2ICAM1ITGAL | |
| SCHEMBL936872 | 0.82 | LMNA (0.45) | ALDH1A1GPR84PKMITGB2ICAM1 | |
| SCHEMBL936096 | 0.81 | GPR84 (0.41) | ALDH1A1GPR84ITGB2ICAM1ITGAL | |
| SCHEMBL935586 | 0.80 | POLB (0.51) | ALDH1A1GPR84PPARGPPARAITGB2 | |
| SCHEMBL957431 | 0.78 | GPR84 (0.41) | ALDH1A1GPR84ITGB2ICAM1ITGAL | |
| SCHEMBL955533 | 0.78 | GPR84 (0.41) | ALDH1A1GPR84ITGB2ICAM1ITGAL | |
| SCHEMBL935339 | 0.78 | GPR84 (0.41) | ALDH1A1GPR84ITGB2ICAM1ITGAL | |
| SCHEMBL936027 | 0.78 | GPR84 (0.42) | GPR84PPARGPPARAITGB2ICAM1 | |
| SCHEMBL28538348 | 0.78 | ALDH1A1 (0.48) | ALDH1A1PKMPPARGPPARALMNA | |
| SCHEMBL29283522 | 0.78 | ALDH1A1 (0.48) | ALDH1A1PKMPPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |